Von Willebrand disease III (Nederlandse Kooikerhondje)

Body function:

Heart & Blood

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Von Willebrand disease III is a genetic condition associated with 3 different genetic mutations of the vWF gene. Different mutations affect different breeds, including the Dutch Kooiker. Dogs with the condition lack proper levels of von Willebrand factor, which helps with blood clotting.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Nederlandse Kooikerhondje

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What does this mean for a dog with this trait?

There is no known treatment for von Willebrand disease III. It’s important to inform veterinarians of the condition before surgeries so they can have extra blood on hand in case a transfusion is needed.

Symptoms

Symptoms of von Willebrand disease III include severe and prolonged bleeding after injuries and surgery. Dogs may also experience excessive bruising from minor trauma. Without medical intervention, bleeding can be so severe that it leads to death.

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