Hereditary Vitamin D-Resistant Rickets

Body function:

Skeletal & Joint

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Hereditary Vitamin D-Resistant Rickets (HVDRR) is a rare genetic disorder in dogs that affects the body's ability to properly use vitamin D, leading to severe issues with bone development and calcium regulation.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Pomeranian

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

Care for a dog with HVDRR typically includes calcium supplements and active vitamin D to maintain normal calcium levels. However, even with treatment, these dogs have persistent low calcium levels, requiring careful monitoring by a vet. Prognosis can be challenging due to the nature of the disorder.

Symptoms

A dog with HVDRR may show abnormal bone growth, weakness, and alopecia symptoms. Despite high vitamin D levels, the dog's body remains resistant to it, leading to persistent low calcium levels, which can result in serious health issues. Dogs with HVDRR typically display symptoms from a young age, including stunted growth, lameness, and bone deformities.

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