Hyperuricosuria
List of affected breeds:
Genetic research has linked this gene and condition in the following breeds:
Dalmatian, Majorca Mastiff
What does this mean for a dog with this trait?
Managing hyperuricosuria involves a combination of dietary and medical interventions. Dogs diagnosed with this condition should be closely monitored by a veterinarian who can recommend a special diet to help manage uric acid levels and prevent stone formation. Regular veterinary check-ups are essential to monitor for the development of urinary stones or other complications. In cases where stones form, surgical intervention or other treatments may be necessary to remove them and alleviate any associated pain or blockage.
Symptoms
Dogs with hyperuricosuria often exhibit symptoms related to urinary tract problems. Common signs include frequent urination, blood in the urine, and straining while urinating. Affected dogs may also show a loss of appetite, lethargy, weakness, vomiting, and pain. The presence of urinary stones can lead to complications such as urinary tract infections or, in severe cases, urethra blockage. While the condition can affect both male and female dogs, males are more prone to urinary obstruction due to their anatomical differences. It is important to note that not all dogs with the gene mutation will show clinical signs, but they will still have elevated uric acid levels.
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Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.