Thrombopathia (American Eskimo Dog)

Body function:

Heart & Blood

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Thrombopathia is a genetic disorder affecting American Eskimo Dog caused by a mutation in the RASGRP1 gene. It prevents blood from clotting correctly. This condition is inherited in the autosomal recessive fashion, meaning both parents must be carriers of the mutation for the offspring to be affected.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

American Eskimo Dog

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What does this mean for a dog with this trait?

There is no known cure for thrombopathia. Dogs with the condition may require additional supervision, as even small traumas can lead to deadly levels of blood loss. Veterinarians should also be informed before any major surgery to have extra blood on hand in case a transfusion is needed.

Symptoms

Thrombopathia is typically first diagnosed during teething, as dogs may experience excessive bleeding when new teeth come in. Other symptoms include spontaneous nose or gum bleeds and significant dark purple bruising on the body.

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