T-zone Lymphoma (Golden Retriever)

Body function:

Immune & Autoimmune

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T-zone lymphoma (TZL) is a type of T-cell lymphoma in dogs known for its slow progression. Unlike more aggressive lymphomas, TZL allows for a median survival time of up to several years; chemotherapy generally doesn't improve these outcomes. This type of lymphoma is relatively common, particularly among certain breeds like Golden Retrievers. Dogs with TZL often show no signs of illness, and the condition is frequently discovered incidentally during routine examinations or procedures.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Golden Retriever

A brown dog with floppy ears is looking up at the camera with its mouth open and tongue out. The dog is standing in a field of tall grass.

What does this mean for a dog with this trait?

Care for dogs with T-zone lymphoma focuses on managing symptoms rather than aggressive treatment as the condition progresses slowly. Monitoring and periodic veterinary evaluations are essential to track the disease, with some cases requiring surgery, chemotherapy, or radiation to manage specific symptoms.

Symptoms

Symptoms of T-zone lymphoma can include the enlargement of lymph nodes, particularly around the head, but affected dogs typically don't display significant changes in their behavior. Some dogs may develop lesions.

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