Cone-Rod Dystrophy 4

Body function:

Eyes

In collaboration with

CRD-NPHP4 and cord1-PRA (also known as CRD4 or CRD SWD) are the two known types of Cone-Rod Dystrophy in dachshunds. Genetic mutations in the RPGRIP1 gene contribute to progressive retinal atrophy (PRA). These mutations are autosomal recessive, meaning both parents must carry the mutation for the offspring to have symptoms.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Miniature Dachshund

A brown and white dog with floppy ears is looking up at the camera with a big smile and its tongue hanging out.

What does this mean for a dog with this trait?

There is no cure for PRA or CRD. Instead, care focuses on maintaining a consistent and safe environment to help dogs adapt to their vision loss. Regular eye exams can also be helpful, and genetic testing can inform breeding decisions.

Symptoms

Symptoms of CRD in dachshunds include the loss of color vision, reduced visual acuity, day blindness, aversion to bright light, loss of peripheral vision, and eventual total blindness.

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