Cone-Rod Dystrophy 2

Body function:

Eyes

In collaboration with

The gene CRD2 causes early-onset retinal degeneration and blindness in Pitbull Terriers. Dogs with two copies of the IQCB1 gene will develop severe vision loss by early adulthood. This condition is inherited, and both parents must carry the gene for their offspring to be affected.

In collaboration with

List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

American Pit Bull Terrier

A brown and white dog with floppy ears is looking up at the camera with a big smile and its tongue hanging out.

What does this mean for a dog with this trait?

There's no cure for CRD2. Caring for a dog with CRD2 involves creating a safe and supportive environment. Maintain a consistent home layout to help the dog get around more easily and avoid moving furniture too frequently. Provide enough lighting in dim areas to reduce disorientation. Testing early can help prevent this condition in the next generation.

Symptoms

Dogs affected by CRD2 show signs of visual impairment before reaching one year of age. These symptoms may include bumping into objects and hesitancy when moving, especially in low-light conditions. As the retinal degeneration progresses, the dog's vision deteriorates further, leading to blindness by early adulthood.

200+ health condition screenings and counting

Like humans, the science surrounding canines is constantly evolving. The more we learn, the more we are able to make educated decisions when it comes to providing their care they deserve.

Explore conditions

Get even deeper insights with our
Breeds & Health kit

With tests for hundreds of breeds, behavioral traits, and health conditions, understanding your best friend has never been easier.

Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.

Buy a kit