Progressive Rod-Cone Degeneration

Body function:

Eyes

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Progressive rod-code degeneration (PRCD) is an inherited eye condition that affects numerous dog breeds, causing gradual vision loss. This autosomal recessive disorder stems from a mutation in the PRCD gene, impacting photoreceptors responsible for night and day vision. Initially affecting rod cells, then progressing to cones, PRCD advances from night-blindness to complete vision loss.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Cocker Spaniel, American Eskimo Dog, Australian Cattle Dog, Australian Shepherd, Barbet, Chesapeake Bay Retriever, Chihuahua, Chinese Crested, English Cocker Spaniel, Entlebucher Mountain Dog, Finnish Lapphund, Golden Retriever, Karelian Bear Dog, Kuvasz, Labrador Retriever, Lapponian Herder, Elkhound, Nova Scotia Duck Tolling Retriever, Poodle, Small Poodle, Portuguese Podengo, Portuguese Water Dog, Schipperke, Silky Terrier, Spanish Water Dog, Swedish Lapphund, Swedish White Elkhound, Yorkshire Terrier

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What does this mean for a dog with this trait?

While there is no cure for PRCD, proper care can enhance a dog's quality of life. Regular vet checkups can help monitor disease progression. As vision declines, pet parents should maintain a consistent home layout to help their dogs navigate their surroundings.

Symptoms

Symptoms of PRCD emerge gradually, often starting in adolescence or early adulthood. The first sign is difficulty seeing in low light conditions, as rod cells deteriorate. Owners might notice their dogs becoming hesitant in dimly lit areas or bumping into objects at night. As the disease progresses, daytime vision also declines due to cone cell degeneration, affecting the dog's ability to perceive colors and move around in bright light.

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