Early-Onset Progressive Polyneuropathy (Alaskan Malamute)

Body function:

Muscle & Neurological

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Early-onset progressive polyneuropathy Alaskan Malamute type is a genetic condition affecting Alaskan Malamute dogs that leads to the dysfunction of peripheral nerves. As a result, dogs with the condition are unable to send messages from the brain and spinal cord throughout the rest of the body, causing severe lack of coordination.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Alaskan Malamute

A black and white dog with a happy expression is looking up at the camera with its mouth open. The dog's ears are perked up, and it appears to be excited.

What does this mean for a dog with this trait?

There is no cure for early-onset progressive polyneuropathy Alaskan Malamute type. Many find euthanasia to be a compassionate choice for dogs with this condition.

Symptoms

Symptoms of the condition typically appear within the first year and a half of life. Dogs experience muscle atrophy and wasting, decreasing ability to control their voice, and even difficulty breathing. They also have a rounded spine and peculiar “bunny-hopping” gait.

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