Early-Onset Progressive Polyneuropathy (Greyhound)

Body function:

Muscle & Neurological

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Early-onset progressive polyneuropathy Greyhound type is a neurological disorder that affects Greyhound dogs and is caused by a genetic mutation in the NDRG1 gene. The condition causes multiple different nerve types to improperly function and deteriorate, leading to very poor quality of life.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Greyhound

A black and white dog with a happy expression is looking up at the camera with its mouth open. The dog's ears are perked up, and it appears to be excited.

What does this mean for a dog with this trait?

There is no known cure for early-onset progressive polyneuropathy Greyhound type. Many find that euthanasia is a compassionate choice for dogs with the condition.

Symptoms

Symptoms of early-onset progressive polyneuropathy Greyhound type typically appear by the first 9 months of life. Dogs with the condition experience muscle wasting and atrophy, ataxia, and severe exercise intolerance. These dogs also develop a peculiar gait. Overtime, dogs with early-onset progressive polyneuropathy risk developing respiratory failure.

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