Osteosarcoma (Irish Wolfhound)

Body function:

Skeletal & Joint

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Osteosarcoma in Irish Wolfhounds is an aggressive form of bone cancer. Though its exact origins are unknown, research suggests that it may be associated with mutations in the CDKN2A and CDKN2B genes. Osteosarcoma typically begins in the legs and spreads throughout the body quickly.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Irish Wolfhound

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

There is no known cure for osteosarcoma in dogs. In the event that the tumor is caught before metastasis, amputation of the affected limb may stop the spread of the tumor. In cases of metastasis, chemotherapy can extend life for up to a year.

Symptoms

Symptoms of osteosarcoma are usually initially located in a specific limb. Dogs may show signs of swelling and be reluctant to put pressure on that limb. As it spreads, additional symptoms may include weight loss and difficulty breathing. Unfortunately, the condition is ultimately fatal.

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