Osteosarcoma (Greyhound)

Body function:
Skeletal & Joint
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Osteosarcoma is a genetic bone cancer affecting Greyhound dogs. Though the specific genetic mutation is unknown, it appears to be associated with the CDKN2A and CDKN2B genes. The cancer typically begins in long bones and metastasizes rapidly.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Greyhound

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

There is no known cure for osteosarcoma. The condition may be treated through chemotherapy, which can extend life between 6 months and 1 year. If caught early, surgical amputation may stop the spread of the tumor.

Symptoms

Symptoms of osteosarcoma in Greyhounds typically first appear as signs of pain in a specific limb. Dogs may be reluctant to put pressure on this limb. This may be accompanied by a noticeable mass or swelling of the limb. As the cancer progresses, dogs can experience loss of appetite and difficulty breathing. Unfortunately, the condition often results in death.

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