Osteogenesis Imperfecta (Beagle)

Body function:

Skeletal & Joint

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Osteogenesis imperfecta Beagle type is a genetic disorder affecting Beagles caused by a mutation in the COL1A2 gene. The condition affects a dog’s collagen development, creating highly fragile bones. It’s inherited in the autosomal recessive fashion, meaning both parents must be carriers for a litter to be affected.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Beagle

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

There is no known cure for osteogenesis imperfecta Beagle type. Most choose euthanasia as a compassionate choice for dogs with the condition.

Symptoms

Symptoms of osteogenesis imperfecta Beagle type include extremely brittle and thin bones that break very easily and don’t heal properly. They also include loose joints, brittle teeth, and small size.

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