Fetal Onset Neuroaxonal Dystrophy

Body function:

Muscle & Neurological

In collaboration with

Fetal onset neuroaxonal dystrophy (FNAD) is a genetic neuromuscular disorder in Giant Schnauzers caused by a mutation in the MFN2 gene. This condition disrupts the function of motor nerve cells, leading to severe underdevelopment of muscles and organs in affected puppies. The disorder is autosomal recessive.

In collaboration with

List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Giant Schnauzer, Beagle

A black and white dog with a happy expression is looking up at the camera with its mouth open. The dog's ears are perked up, and it appears to be excited.

What does this mean for a dog with this trait?

There is no treatment for FNAD, and affected puppies do not survive beyond birth. Prevention through genetic testing is the primary approach to treat this condition since it allows breeders to identify carrier dogs and avoid breeding them together.

Symptoms

Puppies affected by FNAD are born with severe respiratory issues due to underdeveloped lungs, and they often die at birth from respiratory failure. Their joints are contracted and immobile, and they exhibit a curved spine. Since the disorder affects the development of the nervous system in utero, these puppies are unable to move or breathe on their own.

200+ health condition screenings and counting

Like humans, the science surrounding canines is constantly evolving. The more we learn, the more we are able to make educated decisions when it comes to providing their care they deserve.

Explore conditions

Get even deeper insights with our
Breeds & Health kit

With tests for hundreds of breeds, behavioral traits, and health conditions, understanding your best friend has never been easier.

Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.

Buy a kit