Hereditary Nasal Parakeratosis

Body function:

Skin

In collaboration with

Hereditary Nasal Parakeratosis is a genetic disorder affecting Labrador Retrievers caused by a mutation in the SUV39H2 gene. It affects cells in the nose and predisposes dogs toward bacterial infections. This condition is inherited in the autosomal recessive fashion, meaning both parents must be carriers for a litter to be affected.

In collaboration with

List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Labrador Retriever

A yellow dog is looking up at the camera with a big smile and its tongue hanging out.

What does this mean for a dog with this trait?

There is no known cure for hereditary nasal parakeratosis. Treatments include topical ointments and serums to keep the nose hydrated and prevent cracking. Antibiotics may also be prescribed to treat associated infections.

Symptoms

Symptoms of hereditary nasal parakeratosis typically appear between 6 months and 1 year of age and include dry, rough crust in and on the nasal area. Cracks commonly form in the surface of the nose, which can become painful and infected. Severity of symptoms fluctuates throughout life.

200+ health condition screenings and counting

Like humans, the science surrounding canines is constantly evolving. The more we learn, the more we are able to make educated decisions when it comes to providing their care they deserve.

Explore conditions

Get even deeper insights with our
Breeds & Health kit

With tests for hundreds of breeds, behavioral traits, and health conditions, understanding your best friend has never been easier.

Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.

Buy a kit