Canine Multifocal Retinopathy 3

Body function:
Eyes
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Canine multifocal retinopathy 3 is a progressive eye disease that affects Finnish Lapphund, Lapponian Herder, and Swedish Lapphund dogs. It’s caused by a deletion mutation in the Bestrophin 1 gene that affects the formation of proteins. Dogs with this mutation suffer from retinal detachment, typically between 9 months and 2 years of age. In order for a dog to be affected, it must have 2 copies of the mutation.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Finnish Lapphund, Lapponian Herder

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What does this mean for a dog with this trait?

Canine multifocal retinopathy 3 has no known cure or treatment, and the disease typically stops progressing around 2 years of age. Dogs experiencing visual impairment may be helped by additional lighting, especially at night, and increased supervision.

Symptoms

Retinal detachment caused by canine multifocal retinopathy 3 can cause fluid buildup in the eye. This typically appears as gray, tan, orange, or pink spots in the back of the eye that look like blisters. This fluid buildup can lead to vision impairment.

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