Canine Multifocal Retinopathy 2

Body function:
Eyes
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Canine multifocal retinopathy 2 is an eye disease caused by a mutation in the Bestrophin 1 gene. It causes retinal detachment, typically appearing around 3 months of age and progressing slowly until 1 year old. This disease specifically affects Coton de Tulear dogs and is inherited in the autosomal recessive fashion, meaning both parents must be carriers of the mutation for a puppy to be affected.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Coton De Tulear

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What does this mean for a dog with this trait?

There is no known treatment for canine multifocal retinopathy 2. If a dog is experiencing reduced vision due to canine multifocal retinopathy 2, it may be a good idea to add additional lighting, especially at night, and additional supervision.

Symptoms

Dogs experiencing canine multifocal retinopathy 2 will experience fluid buildup in spots where their retina has detached, leading to gray, tan, orange, or pink “blisters” in the back of the eye. Dogs with this disease may have reduced vision.

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