Lundehund Syndrome

Body function:

Skeletal & Joint

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Lundehund syndrome is a genetic disease affecting Norwegian Lundehund dogs caused by a mutation in the LEPREL1 gene. It is a gastrointestinal disease that causes decreased levels of protein and calcium.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Lundehund

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

There is no known cure for Lundehund syndrome, but several treatments are used to help with symptoms. Medications like NSAIDs may help with pain, and a specialized diet may help normalize the digestive tract. In severe cases where quality of life is affected, euthanasia may be the most compassionate choice.

Symptoms

Signs of Lundehund syndrome may appear anywhere from 2 years to 10 years of age. Dogs experience extreme gastrointestinal distress, like diarrhea, weight loss, hair loss, and vomiting. Dogs may also collect fluid in the abdomen and experience swollen limbs. Symptoms can range from mild to extremely severe.

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