Ichthyosis (Great Dane)

Body function:

Skin

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Ichthyosis is a genetic skin disorder. In Great Danes, it is caused by a mutation in the SLC27A4 gene. The condition affects the outer layer of the skin, causing it to develop improperly. This condition is inherited in the autosomal recessive fashion, meaning both parents must be carriers for a litter to be affected.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Great Dane

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What does this mean for a dog with this trait?

There is no known cure for ichthyosis. Its symptoms may be treated with medicated shampoos and rinses, which may help hydrate the skin and reduce itching.

Symptoms

Symptoms of ichthyosis include large, dark, scaly patches on the skin and thickening of foot pads. Dry patches may crack, leading to pain and discomfort.

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