Ichthyosis

Body function:

Skin

In collaboration with

Ichthyosis in American Bulldogs is a genetic skin condition caused by a mutation in the NIPAL4 gene. The condition causes flaky and scaly skin. This condition is inherited in the autosomal recessive fashion, meaning both parents must be carriers for a litter to inherit the mutation.

In collaboration with

List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

American Bulldog, American Bully

A yellow dog is looking up at the camera with a big smile and its tongue hanging out.

What does this mean for a dog with this trait?

There is no known cure for ichthyosis. Skin may be soothed with medicated shampoos or rinses. Antibiotics may also be prescribed for any secondary infections that arise.

Symptoms

Signs of ichthyosis typically appear around 2 weeks of age. They include large, oily flakes and scaly skin. Dogs with the condition are susceptible to secondary infections of the skin, ear, and footpads as a result of the condition.

200+ health condition screenings and counting

Like humans, the science surrounding canines is constantly evolving. The more we learn, the more we are able to make educated decisions when it comes to providing their care they deserve.

Explore conditions

Get even deeper insights with our
Breeds & Health kit

With tests for hundreds of breeds, behavioral traits, and health conditions, understanding your best friend has never been easier.

Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.

Buy a kit