Epidermolytic Hyperkeratosis

Body function:

Skin

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Epidermolytic hyperkeratosis is a skin disorder affecting dogs that is caused by a mutation of the KRT10 gene. The condition prevents the epidermis, or outer layer of skin, from correctly forming. The condition was originally found in the Norfolk terrier but affects various breeds.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Norfolk Terrier

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What does this mean for a dog with this trait?

There is no known cure for epidermolytic hyperkeratosis. The condition may be soothed with anti-dandruff shampoo and moisturizers, but generally, it is a complex disorder to manage.

Symptoms

Symptoms of epidermolytic hyperkeratosis include dark and hyperpigmented skin with large flakes that shed. Skin irritation most commonly occurs in areas where skin touches or rubs together, like the groin and between the front legs and torso.

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