Factor IX Deficiency (Lhasa Apso)

Body function:

Heart & Blood

In collaboration with

Factor IX Deficiency, or Hemophilia B, is a genetic blood disorder specifically identified in Lhasa Apso dogs. It is caused by a deletion mutation in the F9 gene. This mutation leads to the production of less than 1% of normal Factor IX levels, resulting in severe bleeding issues. Hemophilia B is an X-linked recessive trait, making it most common in males.

In collaboration with

List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Lhasa Apso

A white dog with a friendly expression is looking up at the camera with its mouth open and tongue out. The dog's fur is slightly ruffled.

What does this mean for a dog with this trait?

There is no treatment for this disorder. During and after surgeries, affected dogs may require blood or platelet transfusions to manage bleeding. It's also important to avoid activities that could cause injuries.

Symptoms

In Lhasa Apsos, symptoms include easy and excessive bruising, frequent nosebleeds, and blood-filled masses (hematomas) that develop under the skin and within muscles even after mild trauma. Affected dogs may also experience internal bleeding and have bloody or dark tarry feces. Lameness or stiffness can occur if bleeding in the joints is present. Additionally, there is a significant risk of severe and prolonged bleeding after surgery or trauma.

200+ health condition screenings and counting

Like humans, the science surrounding canines is constantly evolving. The more we learn, the more we are able to make educated decisions when it comes to providing their care they deserve.

Explore conditions

Get even deeper insights with our
Breeds & Health kit

With tests for hundreds of breeds, behavioral traits, and health conditions, understanding your best friend has never been easier.

Note: A genetic test is not a diagnosis for disease. Consult any concerns with your vet.

Buy a kit