Dermatomyositis

Body function:

Muscle & Neurological

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Canine dermatomyositis is a genetic disease associated with 3 different genetic mutations: PAN2, MAP3K7CL, and DRB1. It causes skin lesions and can even progress to muscle lesions. The cause of the condition requires further research.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Collie, Shetland Sheepdog

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What does this mean for a dog with this trait?

Treatment for dermatomyositis can include medications to manage skin lesions and regulate the immune system. They are generally effective, but dogs may experience relapse while on these medications. In severe cases, euthanasia may be the most compassionate option.

Symptoms

Signs of dermatomyositis can appear anywhere from 6 months of age into adulthood. Dogs develop swollen patches on the skin that progress into pustules and ulcers, though typically not painful. Lesions may also develop in the muscles, leading to muscular atrophy.

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