Dental Hypomineralization

Body function:

Skeletal & Joint

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Dental hypomineralization is a condition affecting Border Collies caused by a mutation in the FAM20C gene. The disease disrupts an important protein involved in bone and teeth mineralization, preventing teeth from mineralizing in development. Dental hypomineralization is inherited in the autosomal recessive fashion, meaning both parents must be carriers for offspring to be affected.

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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Border Collie

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

There is no known cure for dental hypomineralization. Treatment includes removing damaged teeth and treating symptoms like pain and inflammation or any infection that arises.

Symptoms

Signs of dental hypomineralization include excessive wear of teeth, like brown discoloration, cracked tooth enamel, inflammation, and even loss of teeth. Dogs may be subject to pain or oral infection due to the condition.

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