Cystinuria (Miniature Pinscher)

Body function:
Metabolic & Digestive
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Cystinuria is a kidney disease that occurs in Miniature Pinschers due to a mutation on the SLC7A9 gene. The condition causes significant levels of cystine to accumulate in the urine, which can lead to crystals and stones in the urinary tract. If left untreated, these formations can block the urethra.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Miniature Pinscher

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What does this mean for a dog with this trait?

Cystinuria can be treated with prescription diets and medications that aim to lower the acidity of the urine, making it harder for cystine crystals to form. If stones are blocking the urinary tract, there are both non-surgical and surgical procedures that can help.

Symptoms

Symptoms of cystinuria include difficulty urinating, straining when urinating, and blood in the urine. Dogs suffering from cystinuria may only be able to pass small amounts of urine at a time. If left untreated, dogs with cystinuria can be susceptible to urinary tract infections, kidney infections, and even death.

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