Chondrodysplasia

Body function:
Skeletal & Joint
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Chondrodysplasia is a group of dwarfism conditions that can affect Norwegian Elkhounds and Karelian Bear Dogs. It's caused by a mutation in the ITGA10 gene, which disrupts normal cartilage and bone development, leading to a range of skeletal abnormalities.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Chinook, Karelian Bear Dog, Elkhound

A brown dog is sitting on its hind legs with its front paw raised. The dog is looking up at the camera with a hopeful expression.

What does this mean for a dog with this trait?

Managing chondrodysplasia in dogs involves supportive care aimed at maintaining their quality of life and preventing secondary complications. Pet parents should work with their vet to monitor the progression of the disease and to address issues like arthritis, which may develop due to abnormal bone alignment. Keeping affected dogs at a healthy weight is crucial to reduce strain on the joints and minimize discomfort. Although there is no cure for chondrodysplasia, careful management and a tailored care plan developed in partnership with a veterinarian can help affected dogs live comfortably.

Symptoms

Dogs affected by chondrodysplasia exhibit a range of skeletal issues noticeable from an early age. These include shortened limbs due to abnormal bone growth, which gives the dogs a characteristic "knock-knee" appearance, and bowed legs. The outer digits of their paws are often shorter than usual, and many affected dogs also develop hip dysplasia, leading to muscle atrophy in the hind limbs. As the condition progresses, these dogs may become prone to arthritis, which can further impact their mobility and quality of life. The limbs of affected dogs are typically about 10 centimeters shorter than those of unaffected dogs of the same breed.

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