Amelogenesis Imperfecta

Body function:
Skeletal & Joint
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Amelogenesis imperfecta (AI) is a genetic disorder affecting the development of tooth enamel in Italian Greyhounds. A mutation in the ENAM gene causes this condition. Dogs with AI have misshapen teeth with rough, irregular surfaces and gray or brown spots. The disorder affects both baby and permanent teeth, leading to premature enamel wear and the appearance of larger gaps between the teeth. While AI significantly impacts the appearance and structure of the teeth, it does not typically increase the risk of periodontal disease or dental cavities.
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List of affected breeds:

Genetic research has linked this gene and condition in the following breeds:

Italian Greyhound

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What does this mean for a dog with this trait?

Managing Amelogenesis imperfecta in Italian Greyhounds involves regular dental care to monitor and address any potential issues arising from the defective enamel. In severe cases, treatment may include dental restorations to protect the remaining enamel and improve the dog's comfort.

Symptoms

The primary symptoms of Amelogenesis imperfecta in Italian Greyhounds include misshapen and discolored teeth, with enamel that is thin, rough, and prone to excessive wear. Affected dogs often have smaller, more pointed teeth than usual, with noticeable gaps between them, even at a young age. The discoloration of the teeth is typically gray or brown, and the enamel may be pitted or grooved. These symptoms are usually noticeable when the baby teeth erupt and continue as the permanent teeth develop. Despite these enamel defects, affected dogs rarely suffer from broken teeth or dental cavities.

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