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Thrombopathia (Cavalier King Charles Spaniel)

Body function:
Heart & Blood
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Thrombopathia is a genetic disorder affecting Cavalier King Charles Spaniels, caused by a mutation in the RASGRP2 gene. This condition causes platelets to be unable to aggregate, preventing blood from clotting. The condition is inherited in an autosomal recessive manner, meaning both parents must carry the gene for a dog to be affected.
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