Rod-cone dysplasia 1 (RCD1)
Rod-cone dysplasia 1 (RCD1) is a genetic eye disorder specifically affecting Irish Setters and Irish Red and White Setters. This rapidly progressing condition leads to early-onset blindness because of a mutation in the PDE6B gene. RCD1 follows an autosomal recessive inheritance pattern, meaning a dog must inherit one copy from each parent to be affected.