Pyruvate Kinase Deficiency (Pug)
Body function: Heart & Blood
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Pyruvate Kinase Deficiency (PKD) is a genetic condition in which pugs lack the pyruvate kinase enzyme, which helps break down sugar for energy in the body. Without enough of it, red blood cells break down prematurely – a condition known as hemolysis. This means that the contents of the red blood cells (including oxygen) can’t reach the bloodstream, causing anemia, low energy, jaundice, and more.
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