Polycystic Kidney Disease
Body function: Reproductive & Urinary
In collaboration with
Polycystic kidney disease (PKD) in Bull Terriers, known as BTPKD, leads to fluid-filled cysts in the kidneys. This condition significantly impairs renal function and often results in chronic renal failure as the dog ages. The disease is associated with a mutation in the Pkd1 gene located on CFA06. This mutation results in a change in the Polycystin 1 protein, which is critical for normal kidney function.
In collaboration with