May-Hegglin Anomaly
Body function: Heart & Blood
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May-Hegglin Anomaly (MHA) is a hereditary blood disorder primarily affecting Pugs. It results from a mutation in the MYH9 gene and is autosomal dominant. As a result, if one parent has MHA, there's a 50% chance that each offspring will be affected. MHA is characterized by abnormalities in platelets and neutrophils, leading to potential blood clotting issues. While the condition can cause prolonged bleeding times and bruising, affected dogs often don't show any symptoms.
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