Malignant Hyperthermia
Body function: Immune & Autoimmune
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Malignant hyperthermia is a genetic disorder affecting muscle metabolism in dogs. This condition causes an uncontrollable rise in body temperature and is triggered by severe muscle contractions and stress, certain anesthetics, or drugs. Malignant hyperthermia is linked to a mutation in the RYR1 gene, which disrupts calcium regulation in muscle cells. Breeds like Greyhounds are particularly prone to this condition.
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