L-2-Hydroxyglutaric Aciduria
Body function: Metabolic & Digestive
In collaboration with
L-2-hydroxyglutaric aciduria mutation 1 is a genetic disease primarily affecting Staffordshire Bull Terrier dogs. It’s caused by a mutation in the L2HGDH gene and leaves dogs unable to break down L-2-hydroxyglutaric acid. As a result, L-2-hydroxyglutaric acid builds up in urine, blood, and in the brain, causing brain damage.
In collaboration with