Factor IX Deficiency (Lhasa Apso)
Factor IX Deficiency, or Hemophilia B, is a genetic blood disorder specifically identified in Lhasa Apso dogs. It is caused by a deletion mutation in the F9 gene. This mutation leads to the production of less than 1% of normal Factor IX levels, resulting in severe bleeding issues. Hemophilia B is an X-linked recessive trait, making it most common in males.