Canine Multifocal Retinopathy 1

Canine multifocal retinopathy 1 is an eye disease caused by a mutation of the Bestrophin 1 gene. It typically appears between 3 and 4 months of age and causes the retina to detach, allowing fluid to accumulate beneath the detached retina. This mutation is inherited in the autosomal recessive fashion, meaning both parents must be carriers of the disease for a puppy to be affected. The disease usually stops progressing around 1 year of age.